Jaroslava Halper, MD, PhD
Jaroslava Halper, MD, PhD
Professor of Pathology
Department of Pathology, CVM, 501 DW Brooks Dr., Room 117
PhD, Experimental Pathology, University of Minnesota, Rochester, Minnesota, 1982-1986
Residency, Anatomic Pathology, Mayo Clinic, Rochester, Minnesota, 1982-1986
Residency, Anatomic Pathology, Albert Einstein College of Medicine, Bronx, New York, 1980-1981
MD, University of Toronto, Toronto, Canada, 1977-1980
Medical School, Charles University, Prague, Czechoslovakia, 1972-1976 (escaped in 1976)
Honors / Awards / Achievements
Georgia Medical Licensure
Diplomate, American Board of Pathology, 1984
BMC Veterinary Research (Associate Editor since January 2018)
MCG 2017 Exemplary Teaching Award
Sarbacher, CA, Halper J. 2019. Connective tissue and age-related diseases. Subcell Biochem 91:281-310
Young M, Moshood O, Zhang J, Sarbacher CA, Mueller POE, Halper J. 2018. Does BMP2 play a role in the pathogenesis of equine degenerative suspensory ligament desmitis? BMC Res Notes 11(1):672.
Halper J. 2018. Basic components of vascular connective tissue and extracellular matrix. Adv Pharmacol. 81:95-127. doi: 10.1016/bs.apha.2017.08.012. Epub 2017 Oct 27
Halper J (editor and author of four chapters). Progress in Heritable Soft Connective Tissue Diseases. Series: Advances in Experimental Medicine and Biology Springer SBM, Dordrecht, The Netherlands, 2014.
Yang YH, Ard MB, Halper JT, Barabino GA. 2014. Type I collagen-based fibrous capsule enhances integration of tissue-engineered cartilage with native articular cartilage. Annals Biomed Eng 42:716-726; doi: 10.1007/s10439-013-0958-4.
Kim B, Yoon JH, Zhang J, Mueller POE, Halper J. 2010. Glycan profiling of a defect in decorin glycosylation in equine systemic proteoglycan accumulation, a potential model of progeroid form of Ehlers-Danlos syndrome. Arch Biochem Biophys, 501:221-231.
Halper J, Kim B, Khan A, Yoon JH, Mueller POE. 2006. Degenerative suspensory ligament desmitis as a systemic disorder characterized by proteoglycan accumulation. Biomed Central Veterinary Research 2:12.
Yoon JH, Halper J. 2005. The quantification of chondroitin sulfate by rocket electrophoresis. Anal. Biochem. 344: 158-160.
Halper J, Burt DW, Romanoff MN. 2004. On reassessment of the chicken TGFB4 gene as TGFB1. Growth Factors 22:121-122.
Yoon JH, Brooks R Jr, Zhao J-Z, Isaacs D, Halper J. 2004. The effect of the fluoroquinolone enrofloxacin on avian tendon cell cultures. Arch. Toxicol. 78:599-608.
Yoon JH, Brooks RL Jr, Khan A, Pan H, Bryan J, Zhang J, Budsberg SC, Mueller POE, Halper J. 2004. The effect of enrofloxacin on cell proliferation and proteoglycans in horse tendon cells. Cell Biol. Toxicol. 20:41-54.
Pan H, Halper J. 2003. Cloning, expression and characterization of chicken transforming growth factor β4. Biochem. Biophys. Res. Comm. 303:24-30.
Yoon HJ, Brooks R, Kim YH, Terada M, Halper J. 2003. Proteoglycans in chicken gastrocnemius tendons change with exercise. Arch. Biochem. Biophys. 412:279-286.
Pan H, Halper J. 2003. Regulation of heat shock protein 47 and type I procollagen expression in avian tendon cells. Cell Tissue Res. 311:373-382.
He Z, Ong C, Halper J, Bateman A. 2003. Progranulin is a mediator of the wound response. Nature Medicine 9: 225-229.
Yoon JH, Brooks R Jr, Halper J. 2002. Immunoblotting assays for keratan sulfate. Anal. Biochem. 306:298-304.
Parnell PG, Carter BJ, Halper J. 1993. Purification of epithelial-type transforming growth factor by micro-preparative electrophoresis chromatography. BioTechniques 14:591-594.
Parnell PG, Wunderlich J, Carter B, Halper J. 1992. Transforming growth factor type-e: amino acid analysis and partial amino acid sequence. Growth Factors 7:65-72.
Brown CA, Halper J. 1990. Mitogenic effects of transforming growth factor type e on epithelial and fibroblastic cell lines: comparison with other growth factors. Exp. Cell. Res. 190:233-242.
Halper J. 1990. Specific binding of [3H]heparin to human carcinoma SW-13 and other mammalian cells. Exp. Cell. Res. 187:324-327.
Halper J, Moses HL. 1987. Purification and characterization of a novel transforming growth factor. Cancer Res. 47:4552-4559.
My research has been supported in the past by NIH, American Cancer Society, American Quarter Horse Association, United States Equestrian Foundation, University of Georgia Equine Research Program, UGARF Research Fund Award and more recently by private donations and crowdfunding.
Scholarship & Research
Wound Healing and Tissue Repair
Tendon Physiology and Biochemistry
Equine Degenerative Suspensory Ligament Desmitis