Ken Rosenthal, PhD
Ken Rosenthal, PhD
Professor of Immunology
Russell Hall 157, 1425 Prince Avenue, Athens GA, 30602
BS Chemistry: University of Delaware, Newark Delaware, 1973
MA Biochemistry: University of Illinois, Urbana, Illinois, 1976
PhD Biochemistry: University of Illinois, Urbana, Illinois, 1977
Research Fellow, Tumor Virology: Sidney Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, 1977 – 1979
Honors / Awards / Achievements
Excellence in Scholarship AU/UGA Medical Partnership 2020-2021
M2 Teacher of the Year, 2015, voted by Medical Students, Northeast Ohio Medical University (NEOMED)
Hooder for Graduation, Nominated by Classes 2011, 2012, and 2014, NEOMED College of Medicine
Phi Lamda Sigma Honorary Member, voted by Pharmacy Students Class of 2014, NEOMED
Visiting Professor for Microbiology and Immunology, American University of Antigua College of Medicine 2014
Emeritus Professor, 2013, NEOMED
Liebelt-Wheeler Faculty Excellence Award, 2013, NEOMED
Gender Equity Award, Nominated by Class of 2012, NEOMED
Course Director, Best M2 Course 2011 (Infection and Immunity), NEOMED
Master Teacher of the NEOMED Master Teacher’s Guild, 2010 – Present
Waksman Foundation for Microbiology Lecturer, American Society for Microbiology, 2005 – 2007
American Cancer Society Jr. Faculty Research Award, 1981 – 1984
American Cancer Society Postdoctoral Fellowship, 1977-1979
Storm, D.R., Rosenthal, K.S. and Swanson, P.E. 1977. The Polymyxins and Related Peptide Antibiotics, Ann. Rev. Biochem. 46:723-763.
Rosenthal, K.S., Sokol, M.S., Ingram, R., Subramanian, R. and Fort, R. 1982. Tromantadine: An Inhibitor of Early and Late Events in HSV Replication. Antimicrob. Ag. Chemother. 22:1031-1036. (Translated and reprinted into Spanish).
Walro, D.G. and Rosenthal, K.S. 1997. The Antiviral Xanthate Compound D609 Inhibits HSV-1 Replication and Protein Phosphorylation. Antiviral Research 36:63-72.
Rosenthal, K.S., Shapiro, H.M. 1983. Cell Membrane Potential Changes Following EBV Binding, J. Cell Physiol. 117:39-42.
Rosenthal, K.S., Leuther, M.D. and Barisas, B.G. 1984. HSV Binding and Entry Modulates Cell Surface Protein Mobility, J. Virol. 49:980-983.
Hodnichak, C.M., Turley-Shoger, E. and Rosenthal, K.S. 1984. Visualization of HSV-1 Attachment to Target Cells Using S. aureus as a Morphologic Tag, J. Virol. Meth. 8:191-198.
Bower, J.R., Mao, H. Durishin, C., Rozenbom, E., Detwiler, M., Rempinski, D., Karban, T.L. and Rosenthal, K.S. 1999. Intrastrain Variants of HSV-1 Isolated from a Neonate with Fatal Disseminated Infection Differ in the ICP34.5 Gene, Glycoprotein Processing, and Neuroinvasive Disease. J. Virology 73:3843-3853.
Mao, H., Rosenthal, K.S. 2003. Strain Dependent Structural Variants of Herpes Simplex Virus Type 1 ICP34.5 Determine Viral Plaque Size, Efficiency of Glycoprotein Processing and Viral Release and Neuroinvasive Disease Potential. J. Virol. 77:3409-3417.
SF. Grundfest-Broniatowski , G Tellioglu, KS Rosenthal, J Kang, G Erdodi, B Yalcin, M Cakmak, J Drazba, A Bennett, L Lu, and J P Kennedy. A new bioartificial pancreas utilizing amphiphilic membranes for the immunoisolation of porcine islets: a pilot study in the canine. ASAIO J. 2009 55(4):400-5.
Taylor, P.R., Paustian, C.C., Koski, G.K., Zimmerman, D.H., Rosenthal, K.S.. 2010. Maturation of dendritic cell precursors into IL12 producing DCs by J-LEAPS Immunogens. Cellular Immunology, 262: 1-5
Zimmerman, D.H., Taylor, P.R., Bendele, A., Carambula, R., Duzant, Y., Lowe, V., O’Neill, S.P., Talor, E., Rosenthal, K.S.. 2010. CEL-2000: A Therapeutic Vaccine for Rheumatoid Arthritis Arrests Disease Development and Alters Serum Cytokine / Chemokine Patterns in the Bovine Collagen Type II Induced arthritis in the DBA Mouse Model, Intl Immunopharm. 10: 412-421
Taylor, P.R., Koski, G.K., Paustian, C.C., Bailey, E., Cohen, P.A., Moore, F.B-G., Zimmerman, D.H., Rosenthal, K.S. 2010. J-LEAPS vaccines initiate murine Th1 responses by activating dendritic cells. Vaccine. 28: 5533–5542
Rosenthal KS, Mickecz K, Steiner H, Glant TT, Finnegan A, Carambula R, Zimmerman DH.2015. Rheumatoid arthritis vaccine therapies: Perspectives and lessons from therapeutic ligand epitope antigen presentation system vaccines for models of rheumatoid arthritis. Expert Review of Vaccines 14(6):1-18
Rosenthal KS, Stone S, Koski G, Zimmerman DH. 2017. LEAPS Vaccine Incorporating HER-2/NEU Epitope Elicits Protection That Prevents and Limits Tumor Growth and Spread in a Mouse Model of Breast Cancer. J. Immunology Research, Special Issue Cancer Vaccines. Volume 2017, Article ID 3613505, https://doi.org/10.1155/2017/3613505
K Mikecza, K., Glant, T.T., Markovics, A., Rosenthal, K.S., Kurko, J., Carambula, R.E., Cress, S., Steiner 3rd, H.L., Zimmerman, D.H. 2017. An epitope-specific DerG-PG70 LEAPS vaccine modulates T cell responses and suppresses arthritis progression in two related murine models of rheumatoid arthritis. Vaccine 35: 4048–4056. http://dx.doi.org/10.1016/j.vaccine.2017.05.009
Rosenthal, KS and Zimmerman DH. 2017. J-LEAPS vaccines elicit antigen specific Th1 responses by promoting maturation of type 1 dendritic cells (DC1). Part of a special issue on Dendritic Cells. AIMS Allergy and Immunology. 1(2): 89-100 http://www.aimspress.com/article/10.3934/Allergy.2017.2.89
Reviews in Microbiology and Immunology
Rosenthal K. 2020. Three Properties of SARS-CoV-2 That Promote COVID-19. Infectious Diseases in Clinical Practice: Infect Dis Clin Pract 2020;28: 324–326. DOI: 10.1097/IPC.0000000000000941 , Issn Print: 1056-9103
Chappell MT, Kelly C, Rosenthal KS. 2021. Why Is a Child Not a Mini-Adult for Infections? Infectious Diseases in Clinical Practice: Infect Dis Clin Pract 29: e169–e173 DOI: 10.1097/IPC.0000000000001012
Scott DW, Bond M, Manning TH, Lin-Greenberg A, Rosenthal KS. 2023. How Are Older Adults Different Than Other Adults for Infections. Infect Dis Clin Pract 2023;31: e1197 doi: 10.1097/IPC.0000000000001197
Rosenthal KS, Zimmerman DH, 2022.Vaccine Immunomodulation of Disease: Targeting the Treatment of Autoimmune Diseases. Medical Research Archives, [online] 10(7).https://doi.org/10.18103/mra.v10i7.2910
Rosenthal KS, Baker JB. The immune system through the ages. AIMS Allergy and Immunology, 6(3): 170–187. DOI: 10.3934/Allergy.2022013. AIMS Allergy and Immunology Best Paper Award 2022
Santana E., Rosenthal KS. Ablative treatment of inflammatory and other diseases with Monoclonal Antibodies (Mabs) or Janus Kinases (Nibs) increases risk for infection. Infectious Diseases in Clinical Practice. In Press
Rosenthal, J., Rosenthal, K. 2017. Interactive Journal Club: Teaching an Old Dog New Tricks J Medical Education and Curricular Development. 4:1-6 https://journals.sagepub.com/doi/full/10.1177/2382120517719710
Lazerson J, Rosenthal J, Glaubensklee C, Hunt T, Morgenstern B, Pamidimukkala J, Penn DM, Rosenthal K, Sarsekeyeva M, Wragg S. 2018. Adaptation of the Roseman 6-Point Mastery Learning Model to the College of Medicine Program. Journal of Medical Education and Curricular Development Volume 5: 1–5. http://journals.sagepub.com/doi/full/10.1177/2382120518803111
Previously supported by grants from NIH, foundations, and the pharmaceutical and biotech industry for studies of vaccines, antimicrobials, herpes simplex virus pathogenesis, and development of an artificial pancreas.
Module Co-Director: Foundations Module, 2020
Module Co-Director: Hematology-Oncology, 2020
Large Group Instruction: Phase 2, Immunology of the Organ Systems
Small Group Facilitation: Phase 2
Pre-college science education
Scholarship & Research
Primary author and editor of Medical Microbiology, 1st through 10th editions, Murray, Rosenthal and Pfaller, Elsevier, a successful textbook translated into many languages. Also, Rapid reviews of microbiology and immunology, 1st through 3rd editions (2010), Review of Medical Microbiology (2005), and Medical Microbiology And Immunology Flash Cards, (2005, 2009, 2017).
Author and Editor of Microbiology and Immunology Case Reports, Beyond the Pearls, Elsevier, In Press for 2024.
Research interests include the development of peptide vaccines for the prevention of viral infections and breast cancer and for treatment of breast cancer and rheumatoid arthritis using the LEAPS peptide vaccine platform; Studies of the pathogenesis of herpes simplex virus infections; Development and analysis of antimicrobial molecules.
A primary interest is making medical education fun.