Lynetta J. Jobe, DVM, PhD

  • Associate Professor of Pharmacology and Toxicology

Dr. Jobe is an Associate Professor of Pharmacology at the Medical Partnership. Her major areas of interest are in the pathophysiology and pharmacology of congestive heart failure and biomedical sciences.

Education

1992 Doctor of Veterinary Medicine Tuskegee University
1996 Master of Science Pharmacology NC State University
2002 Doctor of Philosophy Biomedical Sciences Auburn University

Residency

NHBLI Postdoctoral Fellowship Auburn University
Postdoctoral Fellowship, Surgery Emory University

Academic Appointments

2012-Present Associate Professor, AU-UGA Medical Partnership, Athens GA
2010-2012 Assistant Professor, University of Maryland, Princess Anne MD
2003-2010 Assistant Professor, Mercer University, Atlanta GA

More About Lynetta Jobe

Lynetta Jobe, DVM, PhD completed her Bachelor of Science degrees in Animal Science and Biology at North Carolina State University. Following completion of her undergraduate studies, she went on to earn her Doctor of Veterinary Medicine degree from Tuskegee University (1992), Master of Science degree in Pharmacology from North Carolina State University (1996), and Doctor of Philosophy degree from Auburn University (2002).

As a graduate student and National Heart, Lung and Blood Institute postdoctoral fellow, Jobe investigated the pathophysiology of left ventricular remodeling in congestive heart failure. Later, as a postdoctoral fellow in the Department of Surgery at Emory University’s Carlyle Fraser Heart Center, she studied mechanisms of myocardial ischemia-reperfusion injury and myocardial contractile dysfunction, as well as new therapeutic approaches to attenuate myocardial injury resulting from myocardial ischemia, catheter-based angioplasty, and cardiac bypass surgery.

Jobe has previously served as a faculty member at Auburn University, Mercer University, and the University of Maryland Eastern Shore where she was involved in teaching at the undergraduate, graduate, and professional school levels. She joined the Medical Partnership faculty in November 2012.

  • Expertise & Interests

    • Cardiac remodeling
    • Veterinary medicine
    • Pharmacokinetics
  • Selected Publications

    1. Johnson LM, Lankford SM and Bai SA. The Influence of Cimetidine on the Pharmacokinetics of the Enantiomers of Verapamil in the Dog During Multiple Oral Dosing. Journal of Pharmacology and Experimental Therapeutics, Vol. 18, No. 2: pp117-123, 1995.
    2. Johnson LM, Atkins C, Keene B, and Bai SA. Pharmacokinetic and Pharmacodynamic Properties of Conventional and CD-Formulated Diltiazem in Cats. Journal of Veterinary Internal Medicine, Vol. 10, no.5: pp.316-320, 1996.
    3. Bai SA, Lankford SM, and Johnson LM. The Pharmacokinetics of Verapamil Enantiomers in the Dog, Chirality, Vol. 5: pp. 436-442, 1996.
    4. Ryan GJ, Jobe LJ, and Martin RL. Pramlintide in the Treatment of Type 1 and Type 2 Diabetes Mellitus, Clinical Therapeutics, Vol. 27, No.19: pp. 1500-1512, 2005.
    5. Ryan GJ, Smiley D, and Jobe LJ. Diabetes and Hypoganadism. Diabetes Update, Vol.1, Issue 1: pp.1-11, 2006.
    6. Vinten-Johansen J, Jiang R, reeves JG, Deneve J, and Jobe LJ. Inflammation, Proinflammatory Mediators and Ischemia-Reperfusion Injury, Hematology/ Oncology Clinics of North America, Vol 21: pp. 123-145, 2007.
    7. Ryan GJ, Briscoe TA, and Jobe LJ. Review of Pramlintide as Adjunctive Therapy in Treatment of Type 1 and Type 2 Diabetes, Drug Design, Development, and Therapy, Vol. 2: pp. 203-214, 2008.
    8. Jobe LJ, Melendez GC, Levick SP, Du Y, Brower GL, and Janicki JS. TNF-alpha Inhibition Attenuates Adverse Remodeling in a Rat Model of Chronic Volume Overload, American Journal of Physiology, Heart Circulation Physiology, 297 (94): H1462-8, 2009.
    9. Patel N, Richard A, Ubale R, Uddin MN, D’Souza M, Jobe LJ. The Effect of Antisense to NF-κB in an Albumin Microsphere Formulation on the Progression of Left-Ventricular Remodeling Associated with Chronic Volume Overload in Rats, Journal of Drug Targeting, 22 (9): 796-804, 2014
    10. Janicki JS, Brower GL, Carver W, Chancey AL, Forman MF, and Jobe LJ. Role of Mast Cells in Cardiovascular Disease. In Cardiovascular Remodeling and Failure. PK Singal, IMC Dixon, LA Kirshenbaum, NS Dhalla (eds). Kluwer Academic Publishers, Boston, pp. 485-499, 2003
    11. Janicki JS, Brower GL, Chancey AL, Forman MF, and Jobe LJ. Cardiac Mast Cells as Mediators of Ventricular Remodeling. In Interstitial Fibrosis in Heart Failure. FJ Villarreal (ed), Springer, New York, pp. 197-209, 2004.